I don't pay much attention to individual stocks, but looking at my account balances over night and what happens in the next day, its a crap shoot. I think if the markets are up big overnight they are generally more likely than not to open up big and carry through the next day, but quite a lot of times they actually open down and close down (or at least down from what they were up to in the overnights). So if the question is "can I make money by looking at market performances overnight and buying (or selling) at open based on those" I would guess not "alpha" there as peeps on this forum would say - you might, but not more money than doing anything else. Just my antidotal experience from watching.