Quote from Math_Wiz:
Large doses would be anywhere from 5-25g/day. If you've been doing this for several months or more, I'm just curious about your findings... Have you found it super helpful? Have you had lab tests every six months to view your TG/HDL levels,
I assume you want to know the effect of fish oil on tryg and cholesterol levels?
I took normal fish oil (only 1-2 pills) and Niacin (again, low dose) before my blood test for 2 weeks and it did effect it positively, pushing LDL levels and Tryg down by 25%.
Now when you talk pharmaceutical fish oil, I think there are only 2, Lovaza by GSK, and Vascepa. Lovaza is the cleanest fish oil available, and I got a subscription for it and taking 1 pill per day. I assume it is also quite expensive, I get a discount. Its protection has just ran out, so technically others could make it, but I heard the cost of making it is rather high, so I am not sure about copycat fish oil.
Anyhow your mentioned dosage seems incredibly high. Who can take 15-25 pills of it a day and what would be the purpose? If you don't get positive effects with 5g/day, tripling it won't help, IMHO. And again, the good quality fish oil is rather expensive...
If cholesterol control is your goal, I would suggest to take a combination of other pills like Niacin (you need the flushing kind) instead of taking too much of fish oil...
http://en.wikipedia.org/wiki/Lovaza
"Recently in July 2012, Amarin Corporation received FDA marketing approval for Vascepa, also referred to as AMR-101.[5] Vascepa will undoubtedly become a major competitor for Lovaza.[6] In clinicial trials, Vascepa was shown to lower triglycerides; while Lovaza also lowers the triglyceride concentration, Vascepa also lowers LDL-C; Lovaza does not. Lovaza was approved to treat people with very high triglyceride levels (>500 mg/dl), Vascepa is also approved for this market; however the company has also demonstrated that the drug can impact levels in people with high triglyceride (> 200 mg/dl and < 500 mg/dl) levels and will file an sNDA for this indication late in 2012"
Relevant article on both:
http://www.forbes.com/sites/matthew...oil-backlash-wash-out-amarin-pharmaceuticals/
"
The idea that some drugs may improve laboratory values without helping patients is now popular among cardiologists. It has not only hurt prescription niacin, sold by Abbott, but also older triglyceride-lowering drugs called fibrates, also sold by Abbott. And it resulted in a dramatic decrease in the number of prescriptions for Merckâs blockbuster cholesterol pills Zetia and Vytorin, which contain an ingredient that lowers âbad cholesterolâ very differently from the better proven statin drugs like Lipitor, Crestor, and Zocor, which Vytorin also contains."