I live in NYC. People here are nuts pedestrians. I'd worry about an angry asshole sitting in front of an auto car, because it won't know what to do. I assume the passenger would have to manually solve that situation.
Using GPS here is totally fine for driving. If all cars were relayed I'd imagine it's be even better; imagine no need for traffic lights because all cars know where the other is and are working in tandem...
I am not thinking about driverless taxis yet and taxi unions. Let's see what happens to long distance trucking and trucking unions first.
Most of trucking is non-union now, and although GPS would be more cost effective, most trucks have Qualcomm computers and those have delays all the time, specialized Trucking GPS units to keep you headed in right direction fail to work at times putting drivers on wrong roads due to changes in weight restrictions or low bridges or snow bridges like in New York City(bridges say they are 12'6" so many new drivers are unaware this means underpasses are based on winter conditions and are really 13'6" plus when snow not present). Some of GPS units will put truck in middle of rivers. I doubt truckstops will be going back to filling up trucks with fuel when they run low nor I doubt they going to add extras for non-human trucks, really not great deal of profit for them in selling fuel, they make more in selling cup of coffee than gallon of diesel. Then of course the hackers will be messing with them like mad, stick a pail on top of GPS unit, and truck goes nowhere. Also, there are many many cities where people actually try to get hit by a truck, usually the cities where every commercial break there is lawyer hawking his services with commercial yelling "Have you been hit by a truck", trucks can't stop on dime and dumb people cut in front and even though trucks now equipped with ABS and sonar, automated breaking on some, 80,000lbs can't stopped in less than football field from 60mph, people think they be tapped by the truck but often times the truck will crush all of them to death.
I have driven truck over one million safe miles, trucking industry making them safer all the time, within two years of all logging will be electronic which will increase wages for many, but there is huge amount of people unwilling to do the job as many youth don't want to work and many people unwilling to leave home for weeks at a time., but when I did it, found it calming and plenty of time to day trade and longer term as well. But for married driver with kids, very hard life, of course great way to get away from that as well, LOL.