It's still harder than it sounds mahram, try getting filled in large size on options or even equity before a date. You need to trade equity- often you need to know more about entry and exit than fundamentals in this game to succeed. this all assumes you are trading size. If your trading 100 shares, then by all means go into the options market. Or for some increased return, mix your position or hedge it with slightly out of the money calls or puts. Attached is an excel file of all biotech trades I made in 2004, long and short. The return is not great, unless you can handle a 20% drawdown, then it would be over 100% return, assuming I upped the risk to the level where 20% drawdowns would take place. I think most people are too conservative to try to do that, but as you can see, the risk management gives a decent return, but its a bit of a shame really, missing out on 100% return because the drawdown could be 20-30%. Thats all my thoughts, hope you try trading this sector.