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It's a commonly-held view that someone will receive the Nobel in physiology or chemistry for CRISPR. It should have been awarded already; the Nobel committee is probably trying to avoid politicizing the ongoing dispute between Zhang's group and Doudna/Charpentier's group. And if we're lucky...

It's all cool guys, I appreciate the excitement on this topic. You heard it from the man! Why buy a depreciating asset when you can lease it from me at the lowest prices on market? :)

I don't have a CBOT B2 for sale. The current BBO is quite close to the historical low if my memory serves me right. Good luck! Yeah.

I'm hoarding a few exchange seats available for lease: 1 x IMM - $1150/mo 1 x IOM - $275/mo 1 x IOM - $275/mo 1 x GEM - $75/mo 1 x NYMEX - $300/mo 1 x NYMEX - $300/mo Non-negotiable. There's not many 1 mo leases advertised on CME's page and I believe I'm offering them below the lowest 1 mo...

They are 5 year NCAs in general. Nothing besides litigation stops you from working for a competitor even after signing a non-compete. Citadel is embroiled in several cases of NCA violations. Optiver and Tibra haven't settled their case either. Also, a 5% management fee tends to be dilutive in...

Edit: Adar, I sent you PM.

That guy reminds me of the hftvol guy, exact same spelling of ".Net" and occasionally switching between proper punctuation and lower case leading character, the exact same arguments (something about Stackoverflow tags being the definitive proof that C# is the best programming language in the...

I'm out of here. No use debating fundamentals with someone who takes personal affront easily.

Thank you.

I'd like to change your mind about the reason for Apple's success. Consider that I've not mentioned a single thing about design or stability throughout this thread - I don't believe those are real advantages offered by Apple although that's what their marketing team would lead most to believe...

All you've proven to us is that: (1) Your standards of "similar" are very low - the $1,500 PC that you described has the specs of an old-generation MacBook Pro/Air. (SATA SSD, i7 quad-core processor, regular memory, single commodity NVIDIA GPU or USB external video card). (2) You have a shaky...

The Mac Pro's SSD is not a "mediocre PCI-E one" as you stipulate. See public benchmarks: http://www.anandtech.com/show/7603/mac-pro-review-late-2013/12 Please open a > GB size .csv in Notepad and look at the process memory usage if you're really interested to have a discussion with me that is...

Seriously, just open an 8 GB text file in Notepad and then see your process memory usage. I'm glad that you concede that read/write is faster on the PCIe SSD, but you're still sweeping the huge disparity under the rug: Sequential read/write throughput via a PCIe SSD is more than 3 times that...

Firstly, the i7-3770 has 4 cores, not 6 as you earlier claimed, which is already a huge flaw in your argument. Secondly, the Xeon E5-1650v2 has 4 memory channels with DDR3-1866 support, therefore it is able to achieve a maximum memory bandwidth of 59.7 GB/s as opposed to 25.6 GB/s on the...

I'm sorry but you have absolutely no idea what you're talking about. An i7 CPU does not perform better than a Xeon E5 CPU. Many important tasks for a financial workstation are I/O bound at the memory bus, e.g. try opening a 10 GB file of comma-separated values on Notepad on your i7 and you'll...

I think you're not very familiar with the specs: Xeon E5-1620v2, $580 2x8 GB PC3-14900 ECC memory, $178 Plextor M6e 256 GB PCIe SSD, $200 2 x Imaginary GPU priced between AMD FirePro W7000 and AMD FirePro W8000, ($750+1300)/2*2 = $2,050 Gigabyte 6PXSV4 (Socket LGA 2011 motherboard with 3x...

Mac is very lenient on old generation AMDs. The cards I'm using were <$40 each actually, probably cheaper nowadays if you can find them, and nevertheless significantly better performance than your latest USB 3.0 external video card. This is a function of both bus limitation, and the speed and...

I don't use this for gaming but I have run Starcraft II on this Mac with moderate settings. You have several ways of doing this, really. 1. Mac Pro (2013) can support 6 regular monitors out-of-the-box using Thunderbolt-to-HDMI adapters. I've done this. 2. If you have an older model...

:confused: Here, I hooked up 6 monitors onto 1 Mac Pro with OS X Mavericks. Multiple display support is decided by hardware capability and device drivers, not the OS. OS X has device drivers for several discrete graphics cards that support multiple displays.

<$250M should be within the domain of Houlihan Lokey.